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Article

From Cytokines to Biomarkers: Mapping the Immunopathology of Inflammatory Bowel Disease.

Cells - 13 Oct 2025

Baum Sarah, Hamedi Kamron, Loftus Caroline, Loftus Gannett, Zhou Emily-Rose, Arce Sergio

Abstract excerpt

Inflammatory bowel disease (IBD) is a chronic immune-mediated condition of the gastrointestinal tract, characterized by dysregulated inflammatory responses throughout the gastrointestinal tract. It includes two major phenotypes, Crohn's disease (CD) and ulcerative colitis (UC), which present with varying gastrointestinal and systemic symptoms. The pathophysiology of IBD is multifactorial including genetic...

Read the complete abstract on PubMed

Topics

Humans
Inflammatory Bowel Diseases
Biomarkers
Cytokines
Animals
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 41148805
DOI: 10.3390/cells14201589
PMCID: PMC12564933

Genes

ATG16L1
CARD9
MPO
NOD2
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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