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Article

A deep-sequencing method detects drug-resistant mutations in the hepatitis B virus in Indonesians.

Intervirology - 1 Jan 2014

Widasari Dewiyani Indah, Yano Yoshihiko, Heriyanto Didik Setyo, Utsumi Takako, Yamani Laura Navika, Rinonce Hanggoro Tri, Wasityastuti Widya, Lusida Maria Inge, Soetjipto, Okada Rina, Murakami Yoshiki, Tanahashi Toshihito, Azuma Takeshi, Hayashi Yoshitake

Abstract excerpt

OBJECTIVE: The long-term administration of a nucleos(t)ide analogue (NA) for the treatment of chronic hepatitis B may encourage the emergence of viral mutations associated with drug resistance. Minor populations of viruses may exist before treatment, but are difficult to detect because of technological limitations. Identifying minor viral quasispecies should be useful in the clinical management of hepatitis B...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25382636
DOI: 10.1159/000366420

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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