Article
Prevalence and types of drug-resistant variants in Chinese patients with acute hepatitis B.
Journal of medical virology - 1 Sept 2015
Su Feifei, Dai Jianyi, Yang Shoufeng, Jiang Xiangao, Cui Xiaoya, Ning Hongye, Li Junhua, Huang Mohe
Abstract excerpt
The presence of therapy-associated hepatitis B virus (HBV) variants is the main drawback of antiviral therapy for HBV infection. Moreover, drug-resistant variants are more insensitive to a second agent and more therapy-associated mutations will be present. To apply better nucleos(t)ide analogues (NA) and reduce the occurrence of resistance, the prevalence and types of drug-resistant mutations in acute hepatitis B...
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