Article
Comparison of Detection Rate and Mutational Pattern of Drug-Resistant Mutations Between a Large Cohort of Genotype B and Genotype C Hepatitis B Virus-Infected Patients in North China.
Microbial drug resistance (Larchmont, N.Y.) - 1 Jun 2017
Li Xiaodong, Liu Yan, Xin Shaojie, Ji Dong, You Shaoli, Hu Jinhua, Zhao Jun, Wu Jingjing, Liao Hao, Zhang Xin-Xin, Xu Dongping
Abstract excerpt
The study aimed to investigate the association of prevalent genotypes in China (HBV/C and HBV/B) with HBV drug-resistant mutations. A total of 13,847 nucleos(t)ide analogue (NA)-treated patients with chronic HBV infection from North China were enrolled. HBV genotypes and resistant mutations were determined by direct sequencing and confirmed by clonal sequencing if necessary. HBV/B, HBV/C, and HBV/D occupied...
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