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Article

Recipient uridine 5'-diphospho-glucuronosyltransferase UGT1A9 c.98T>C variant determines transplanted kidney filtration rate.

Transplantation proceedings - 1 Oct 2014

Pazik J, Ołdak M, Lewandowski Z, Dąbrowski M, Podgórska M, Sitarek E, Malejczyk J, Płoski R, Durlik M

Abstract excerpt

Mycophenolic acid preparations are commonly used in prophylaxis of kidney allograft acute rejection. The medication is metabolized by uridine diphosphate glucuronosyltransferases, mainly UGT1A9 present in liver, kidney, and intestine. The effect of UGT1A9 allelic variants on drug metabolism in healthy volunteers and transplant recipients has been previously evaluated; these studies included the UGT1A9 c.98T>C...

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Source

Identifiers

PMID: 25380893
DOI: 10.1016/j.transproceed.2014.09.077

Variants

rs72551330

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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