Article
Association of UDP-glucuronosyltransferase 1A9 (UGT1A9) gene polymorphism with kidney allograft function.
Annals of transplantation - 1 Jan 2000
Pazik Joanna, Ołdak Monika, Dąbrowski Marcin, Lewandowski Zbigniew, Sitarek Elżbieta, Podgórska Marta, Ważna Ewa, Płoski Rafał, Szmidt Jacek, Chmura Andrzej, Durlik Magdalena, Malejczyk Jacek
Abstract excerpt
BACKGROUND: UDP-glucuronosyltransferases (UGTs) are a group of enzymes involved in the detoxification and excretion of xeno- and endobiotics. Polymorphic variants of the UGT1A9 gene were shown to influence exposition to mycophenolate mophetil (MMF), a common immunosuppressive drug used in kidney allograft recipients. Therefore, the aim of this study was to evaluate an association between key clinical features of...
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