Article
Uridine diphosphate glucuronosyltransferase 2B7 variant p.His268Tyr as a predictor of kidney allograft early acute rejection.
Transplantation proceedings - 1 May 2013
Pazik J, Ołdak M, Lewandowski Z, Podgórska M, Sitarek E, Płoski R, Gałazka Z, Kwiatkowski A, Malejczyk J, Durlik M
Abstract excerpt
BACKGROUND: Uridine diphosphate glucuronosyltransferase (UGT2B7) is responsible for conversion of mycophenolic acid to mycophenolic acyl-glucuronide (acylMPAG). Conflicting data exist regarding the role of UGT2B7 p.His268Tyr (802C>T, rs7439366) variant in the clinical course following organ transplantation. STUDY AIM: The aim of this study was to reveal an association between UGT2B7 p.His268Tyr (802C>T,...
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