Article
Evaluating whole genome sequence data from the Genetic Absence Epilepsy Rat from Strasbourg and its related non-epileptic strain.
PloS one - 1 Jan 2017
Casillas-Espinosa Pablo M, Powell Kim L, Zhu Mingfu, Campbell C Ryan, Maia Jessica M, Ren Zhong, Jones Nigel C, O'Brien Terence J, Petrovski Slavé
Abstract excerpt
OBJECTIVE: The Genetic Absence Epilepsy Rats from Strasbourg (GAERS) are an inbreed Wistar rat strain widely used as a model of genetic generalised epilepsy with absence seizures. As in humans, the genetic architecture that results in genetic generalized epilepsy in GAERS is poorly understood. Here we present the strain-specific variants found among the epileptic GAERS and their related Non-Epileptic Control...
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