Article

CD4 <sup>+</sup> T cells drive corneal nerve damage but not epitheliopathy in an acute aqueous-deficient dry eye model

2024-03-26

Abstract excerpt

Dry eye disease (DED) is characterized by a dysfunctional tear film in which the cornea epithelium and its abundant nerves are affected by ocular desiccation and inflammation. Although adaptive immunity and specifically CD4 + T cells play a role in DED pathogenesis, the exact contribution of these cells to corneal epithelial and neural damage remains undetermined. To address this, we explored the progression of a...

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Identifiers and source

Literature Corpus work: 22b4d888-40b1-51ce-8203-a9170cfd31ab
DOI: 10.1101/2024.03.22.586336

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CD4 <sup>+</sup> T cells drive corneal nerve damage but not epitheliopathy in an acute aqueous-deficient dry eye modelDOI 10.1101/2024.03.22.586336Read

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