Article
KCNQ1OT1 Knock Down Alleviates Hyperosmlity Induced Dry Eye Disease via Inhibiting NLRP3 Inflammsome Activation and IL-1β Release
2021-08-02
Abstract excerpt
<h4>Background: </h4> Long noncoding RNAs (lncRNAs) have been indicated that participate in inflammatory diaeases and age related diseases by regulating physiological and pathological processes directly or indirectly. Evidences have indicated lncRNAs might be involving in dry eye disease which can cause pathological changes of cornea and conjunctiva in ocular surface though inflammatory response. KCNQ1OT1 is a nov...
Topics
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- Allergic Rhinitis and Sensitization
- Cancer-related molecular mechanisms research
- Connexins and lens biology
- Glaucoma and retinal disorders
- Inflammasome and immune disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Ocular Surface and Contact Lens
Identifiers and source
- Literature Corpus work
- 5050ec3c-92e7-5507-ba6e-6e6b6a3f7f6e
- DOI
- 10.21203/rs.3.rs-721954/v1
