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Article

Altered gene expression in slc4a11-/- mouse cornea highlights SLC4A11 roles.

Scientific reports - 22 Oct 2021

Alvarez Bernardo V, Piché Marilyse, Aizouki Carolin, Rahman Fariha, Derry Jonathan M J, Brunette Isabelle, Casey Joseph R

Abstract excerpt

SLC4A11 is a H+/NH3/water transport protein, of corneal endothelial cells. SLC4A11 mutations cause congenital hereditary endothelial dystrophy and some cases of Fuchs endothelial corneal dystrophy. To probe SLC4A11's roles, we compared gene expression in RNA from corneas of 17-week-old slc4a11-/- (n = 3) and slc4a11+/+ mice (n = 3) and subjected to RNA sequencing. mRNA levels for a subset of genes were also...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34686736
DOI: 10.1038/s41598-021-98921-w
PMCID: PMC8536660

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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