Single-nucleotide polymorphisms of nucleotide excision repair genes and their association with overall survival in North Indian lung cancer patients treated with platinum-based doublet chemotherapy.

Abstract excerpt

Background: The aim of the study is to understand the association of Nucleotide excision repair (NER) inter-genetic polymorphic combinations with overall survival (OS) in lung cancer as well as its histological subtypes in the North Indian population. Materials and Methods: Genotyping was performed using polymerase chain reaction-restriction fragment length polymorphism. For survival analysis, the univariate...

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