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Article

Sestrin2 promotes LKB1-mediated AMPK activation in the ischemic heart.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Feb 2015

Morrison Alex, Chen Li, Wang Jinli, Zhang Ming, Yang Hui, Ma Yina, Budanov Andrei, Lee Jun Hee, Karin Michael, Li Ji

Abstract excerpt

The regulation of AMPK in the ischemic heart remains incompletely understood. Recent evidence implicates the role of Sestrin2 in the AMPK signaling pathway, and it is hypothesized that Sestrin2 plays an influential role during myocardial ischemia to promote AMPK activation. Sestrin2 protein was f...

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Identifiers

PMID: 25366347
DOI: 10.1096/fj.14-258814
PMCID: PMC4314228

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25366347-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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