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Article

Crucial role for LKB1 to AMPKalpha2 axis in the regulation of CD36-mediated long-chain fatty acid uptake into cardiomyocytes.

Biochimica et biophysica acta - 1 Mar 2009

Habets Daphna D J, Coumans Will A, El Hasnaoui Mohammed, Zarrinpashneh Elham, Bertrand Luc, Viollet Benoit, Kiens Bente, Jensen Thomas E, Richter Erik A, Bonen Arend, Glatz Jan F C, Luiken Joost J F P

Abstract excerpt

Enhanced contractile activity increases cardiac long-chain fatty acid (LCFA) uptake via translocation of CD36 to the sarcolemma, similarly to increase in glucose uptake via GLUT4 translocation. AMP-activated protein kinase (AMPK) is assumed to mediate contraction-induced LCFA utilization. However...

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Identifiers

PMID: 19159696
DOI: 10.1016/j.bbalip.2008.12.009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19159696-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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