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Article

Stabilization of the β-hairpin in Mason-Pfizer monkey virus capsid protein- a critical step for infectivity.

Retrovirology - 30 Oct 2014

Obr Martin, Hadravová Romana, DoleŽal Michal, KříŽová Ivana, Papoušková Veronika, Zídek Lukáš, Hrabal Richard, Ruml Tomáš, Rumlová Michaela

Abstract excerpt

BACKGROUND: Formation of a mature core is a crucial event for infectivity of retroviruses such as Mason-Pfizer monkey virus (M-PMV). The process is triggered by proteolytic cleavage of the polyprotein precursor Gag, which releases matrix, capsid (CA), and nucleocapsid proteins. Once released, CA assembles to form a mature core - a hexameric lattice protein shell that protects retroviral genomic RNA. Subtle...

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Identifiers

PMID: 25365920
DOI: 10.1186/s12977-014-0094-8
PMCID: PMC4219007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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