Article
A retroviral chimeric capsid protein reveals the role of the N-terminal β-hairpin in mature core assembly.
Journal of molecular biology - 22 Jul 2011
Cortines Juliana R, Monroe Eric B, Kang Sebyung, Prevelige Peter E
Abstract excerpt
The human immunodeficiency virus (HIV) is an enveloped virus constituted by two monomeric RNA molecules that encode for 15 proteins. Among these are the structural proteins that are translated as the gag polyprotein. In order to become infectious, HIV must undergo a maturation process mediated by the proteolytic cleavage of gag to give rise to the isolated structural protein matrix, capsid (CA), nucleocapsid as...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
