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Article

Nucleic Acid Binding by Mason-Pfizer Monkey Virus CA Promotes Virus Assembly and Genome Packaging.

Journal of virology - 1 May 2016

Füzik Tibor, Píchalová Růžena, Schur Florian K M, Strohalmová Karolína, Křížová Ivana, Hadravová Romana, Rumlová Michaela, Briggs John A G, Ulbrich Pavel, Ruml Tomáš

Abstract excerpt

UNLABELLED: The Gag polyprotein of retroviruses drives immature virus assembly by forming hexameric protein lattices. The assembly is primarily mediated by protein-protein interactions between capsid (CA) domains and by interactions between nucleocapsid (NC) domains and RNA. Specific interactions between NC and the viral RNA are required for genome packaging. Previously reported cryoelectron microscopy analysis...

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Share to Capsid Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26912613
DOI: 10.1128/JVI.03197-15
PMCID: PMC4836319

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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