Article

Protease-driven remodeling of stabilization networks during adenovirus assembly

2026-08-04

Abstract excerpt

At least thirteen different proteins form the adenovirus virion, including those bound to the dsDNA genome in the core. To produce infectious particles, the adenovirus protease (AVP) cleaves many of these proteins during genome packaging, using the viral genome as a cofactor. Here, we determine high-resolution structures of two types of adenovirus particles devoid of genome and core proteins and stalled at differe...

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Literature Corpus work: 1ebb5372-911b-59f3-8cd9-0f1585af94dc
DOI: 10.64898/2026.08.04.740336

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