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Article

Acute megakaryoblastic leukemia associated with trisomy 21 demonstrates a distinct immunophenotype

31 Oct 2014

Abstract excerpt

BACKGROUND: Acute megakaryoblastic leukemia (AMKL) is a rare form of acute myeloid leukemia that encompasses three distinct subgroups: children with Down syndrome (DS-AMKL), children without DS (non-DS-AMKL), and adults (adult-AMKL). We hypothesize that the biological differences in the subtypes of AMKL may be reflected in distinct immunophenotypic (IP) features. Our aims were to employ mutiparameter flow...

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PMID: 25361478
DOI: 10.1002/cyto.b.21198

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