Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Myeloid Proliferations Associated with Down Syndrome: Clinicopathologic Characteristics of Forty Cases from Five Large Academic Institutions.

Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2024

van den Akker Tayler A, Liu Yen-Chun, Liu Huifei, Chapman Jennifer, Levine Jennifer M, Weinberg Olga K, Geyer Julia T

Abstract excerpt

INTRODUCTION: The incidence of myelodysplastic syndrome and acute myeloid leukemia is significantly increased in children with Down syndrome (DS). Within the revised 2016 WHO edition, these entities are jointly classified as myeloid leukemia associated with DS (ML-DS). Additionally, infants with DS may develop transient abnormal myelopoiesis (TAM) which is histomorphologically similar to ML-DS. While TAM is...

Topics

Join the communities discussing this publication.

Child
Down Syndrome
Infant
Leukemia, Myeloid, Acute
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 36996802
DOI: 10.1159/000530431
PMCID: PMC10857798

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Myeloid Proliferations Associated with Down Syndrome: Clinicopathologic Characteristics of Forty Cases from Five Large Academic Institutions.PMID 36996802Read ↗

Clinical and biological aspects of myeloid leukemia in Down syndrome.Semantic proximity Read ↗

Hematological disorders in children with Down syndrome.Semantic proximity Read ↗

Advances in molecular characterization of myeloid proliferations associated with Down syndromeSemantic proximity Read ↗

Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome.Semantic proximity Read ↗

Recent advances in the understanding of transient abnormal myelopoiesis in Down syndromeSemantic proximity Read ↗

Acute megakaryoblastic leukemia associated with trisomy 21 demonstrates a distinct immunophenotypeSemantic proximity Read ↗

Myeloid Leukemia in Down SyndromeSemantic proximity Read ↗

Transient leukemia (transient myeloproliferative disorder, transient abnormal myelopoiesis) of Down syndrome.Semantic proximity Read ↗

Complete blood count differences in a cohort of Down syndrome neonates with transient abnormal myelopoiesis screened for GATA1 pathogenic variants.Semantic proximity Read ↗

Sensitive GATA1 mutation screening reliably identifies neonates with Down syndrome at risk for myeloid leukemiaSemantic proximity Read ↗

Transient Abnormal Myelopoiesis and AML in Down Syndrome: an UpdateSemantic proximity Read ↗

Distinctive hematological abnormalities in East Asian neonates and children with Down syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.