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Article

Molecular lesions in childhood and adult acute megakaryoblastic leukaemia.

British journal of haematology - 1 Feb 2012

Hama Asahito, Muramatsu Hideki, Makishima Hideki, Sugimoto Yuka, Szpurka Hadrian, Jasek Monika, O'Keefe Christine, Takahashi Yoshiyuki, Sakaguchi Hirotoshi, Doisaki Sayoko, Shimada Akira, Watanabe Nobuhiro, Kato Koji, Kiyoi Hitoshi, Naoe Tomoki, Kojima Seiji, Maciejewski Jaroslaw P

Abstract excerpt

While acute megakaryoblastic leukaemia (AMKL) occurs in children with (DS-AMKL) and without (paediatric non-DS-AMKL) Down syndrome, it can also affect adults without DS (adult non-DS-AMKL). We have analysed these subgroups of patients (11 children with DS-AMKL, 12 children and four adults with non-DS-AMKL) for the presence of molecular lesions, including mutations and chromosomal abnormalities studied by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22122069
DOI: 10.1111/j.1365-2141.2011.08948.x

Genes

ASXL1
CBL
GATA1
IDH1
JAK2
JAK3
NRAS
RUNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Molecular lesions in childhood and adult acute megakaryoblastic leukaemia.PMID 22122069Read ↗

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