Article
Acute megakaryoblastic leukaemia (AMKL) in children: a comparison of AMKL with and without Down syndrome.
British journal of haematology - 1 Mar 2008
Hama Asahito, Yagasaki Hiroshi, Takahashi Yoshiyuki, Nishio Nobuhiro, Muramatsu Hideki, Yoshida Nao, Tanaka Makito, Hidaka Hirokazu, Watanabe Nobuhiro, Yoshimi Ayami, Matsumoto Kimikazu, Kudo Kazuko, Kato Koji, Horibe Keizo, Kojima Seiji
Abstract excerpt
To characterize childhood acute megakaryoblastic leukaemia (AMKL), we reviewed 45 children with AMKL diagnosed between 1986 and 2005 at Nagoya University Hospital and Japanese Red Cross Nagoya First Hospital. Twenty-four patients (53%) had AMKL associated with Down syndrome (DS-AMKL) and 21 (47%) had non-DS-AMKL. The median age of the DS-AMKL patients was 21 months (range, 8-38 months) and that of non-DS-AMKL...
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