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Article

Screening the expression of ABCB6 in erythrocytes reveals an unexpectedly high frequency of Lan mutations in healthy individuals.

PloS one - 1 Jan 2014

Koszarska Magdalena, Kucsma Nora, Kiss Katalin, Varady Gyorgy, Gera Melinda, Antalffy Geza, Andrikovics Hajnalka, Tordai Attila, Studzian Maciej, Strapagiel Dominik, Pulaski Lukasz, Tani Yoshihiko, Sarkadi Balazs, Szakacs Gergely

Abstract excerpt

Lan is a high-incidence blood group antigen expressed in more than 99.9% of the population. Identification of the human ABC transporter ABCB6 as the molecular basis of Lan has opened the way for studies assessing the relation of ABCB6 function and expression to health and disease. To date, 34 ABCB6 sequence variants have been described in association with reduced ABCB6 expression based on the genotyping of stored...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25360778
DOI: 10.1371/journal.pone.0111590
PMCID: PMC4216114

Genes

ABCB6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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