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Article

A new ABCG2 null allele with a 27-kb deletion including the promoter region causing the Jr(a-) phenotype.

Transfusion - 1 Jun 2015

Ogasawara Kenichi, Osabe Takahiro, Suzuki Yumi, Tsuneyama Hatsue, Isa Kazumi, Kawai Miho, Obara Kumi, Ogiyama Yoshiko, Ito Shoichi, Uchikawa Makoto, Satake Masahiro, Tadokoro Kenji

Abstract excerpt

BACKGROUND: The high-prevalence antigen Jr(a) is carried on the ATP-binding cassette transporter ABCG2. The ABCG2 gene consists of 16 exons and its translation start codon is located on the second exon. Although the occurrence of the Jr(a-) phenotype is rare, several ABCG2 null alleles have been reported. We report a new ABCG2 null allele having a large deletion in this study. STUDY DESIGN AND METHODS: The Jr(a)...

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Share to ATP Binding Cassette Transporter, Subfamily G, Member 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25522810
DOI: 10.1111/trf.12969

Genes

ABCG2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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