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Article

Combined effects of hepatocyte nuclear factor 4α and constitutive androstane receptor on stable warfarin doses.

Pharmacogenetics and genomics - 1 Jan 2015

Moon Jung Yeon, Lee Kyung Eun, Chang Byung Chul, Jeong Eurim, Jeong Hotcherl, Gwak Hye Sun

Abstract excerpt

A possible association between the combination of genetic variations in hepatocyte nuclear factor 4α (HNF4α) and constitutive androstane receptor (CAR) and the stable doses of warfarin was examined in patients from the Ewha-Severance Treatment (EAST) Group of Warfarin. Around 42.5% of the overall interindividual variability in warfarin dose requirements was explained by the multivariate regression model; the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2C9

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Source

Identifiers

PMID: 25356900
DOI: 10.1097/FPC.0000000000000103

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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