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Article

FISH analysis of PTEN in endometrial carcinoma. Comparison with SNP arrays and MLPA.

Histopathology - 1 Sept 2014

Maiques Oscar, Cuevas Dolors, García Dios Diego Andrés, Coenegrachts Lieve, Santacana Maria, Velasco Ana, Romero Marta, Sónia Gatius, Lambrechts Diether, Dolcet Xavier, Amant Frederic, Matias-Guiu Xavier

Abstract excerpt

AIMS: To check the usefulness of a standardized protocol of PTEN FISH in 31 endometrial carcinomas (ECs) in comparison with SNP array (SNPA), multiplex ligation-dependent probe amplification (MLPA), and immunohistochemistry. METHODS AND RESULTS: Fluorescence in-situ hybridization analysis showed two PTEN copies in 17 cases, three copies in nine cases, hemizygous deletion in two cases, and diverse cell populations...

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Topics

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Share to Carcinoma, Endometrioid
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Dosage

Share to Genes, Tumor Suppressor

Share to In Situ Hybridization, Fluorescence

Share to Multiplex Polymerase Chain Reaction

Share to PTEN Phosphohydrolase

Share to Reproducibility of Results

Source

Open in PubMed Open full text

Identifiers

PMID: 25353038
DOI: 10.1111/his.12396
PMCID: PMC4282383

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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