Article
No evidence of association between common European mitochondrial DNA variants in Alzheimer, Parkinson, and migraine in the Spanish population.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jan 2015
Fachal Laura, Mosquera-Miguel Ana, Pastor Pau, Ortega-Cubero Sara, Lorenzo Elena, Oterino-Durán Agustín, Toriello María, Quintáns Beatriz, Camiña-Tato Montse, Sesar Angel, Vega Ana, Sobrido María-Jesús, Salas Antonio
Abstract excerpt
Certain mitochondrial DNA (mtDNA) variants and haplogroups have been found to be associated with neurological disorders. Several studies have suggested that mtDNA variation could have an etiologic role in these disorders by affecting the ATP production on high-energy demanding organs, such as the brain. We have analyzed 15 mtDNA SNPs (mtSNPs) in five cohorts of cases presenting Alzheimer disease (AD), Parkinson...
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