Article
Mitochondrial genome-wide association study of migraine - the HUNT Study.
Cephalalgia : an international journal of headache - 1 May 2020
Børte Sigrid, Zwart John-Anker, Skogholt Anne Heidi, Gabrielsen Maiken Elvestad, Thomas Laurent F, Fritsche Lars G, Surakka Ida, Nielsen Jonas B, Zhou Wei, Wolford Brooke N, Vigeland Magnus D, Hagen Knut, Kristoffersen Espen Saxhaug, Nyholt Dale R, Chasman Daniel I, Brumpton Ben M, Willer Cristen J, Winsvold Bendik S
Abstract excerpt
BACKGROUND: Variation in mitochondrial DNA (mtDNA) has been indicated in migraine pathogenesis, but genetic studies to date have focused on candidate variants, with sparse findings. We aimed to perform the first mitochondrial genome-wide association study of migraine, examining both single variants and mitochondrial haplogroups. METHODS: In total, 71,860 participants from the population-based Nord-Trøndelag...
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