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Article

Validation of DNA Methylation to Predict Outcome in Acute Myeloid Leukemia by Use of xMELP

28 Oct 2014

Abstract excerpt

BACKGROUND: Epigenetic dysregulation involving alterations in DNA methylation is a hallmark of various types of cancer, including acute myeloid leukemia (AML). Although specific cancer types and clinical aggressiveness of tumors can be determined by DNA methylation status, the assessment of DNA methylation at multiple loci is not routinely performed in the clinical laboratory. METHODS: We recently described a...

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PMID: 25348669
DOI: 10.1373/clinchem.2014.229781

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