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Validation of DNA Methylation Biomarkers for Diagnosis of Acute Lymphoblastic Leukemia

15 May 2014

Abstract excerpt

BACKGROUND: DNA methylation biomarkers capable of diagnosis and subtyping have been found for many cancers. Fifteen such markers have previously been identified for pediatric acute lymphoblastic leukemia (ALL). Validation of these markers is necessary to assess their clinical utility for molecular diagnostics. Substantial efficiencies could be achieved with these DNA methylation markers for disease tracking with...

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PMID: 24829271
DOI: 10.1373/clinchem.2013.219956

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