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Article

Oxidative Stress, Mutations and Chromosomal Aberrations Induced by In Vitro and In Vivo Exposure to Furan.

International journal of molecular sciences - 7 Sept 2021

Russo Maria Teresa, De Luca Gabriele, Palma Nieves, Leopardi Paola, Degan Paolo, Cinelli Serena, Pepe Gaetano, Mosesso Pasquale, Di Carlo Emma, Sorrentino Carlo, Musiani Piero, Crebelli Riccardo, Bignami Margherita, Dogliotti Eugenia

Abstract excerpt

Furan is a volatile compound that is formed in foods during thermal processing. It is classified as a possible human carcinogen by international authorities based on sufficient evidence of carcinogenicity from studies in experimental animals. Although a vast number of studies both in vitro and in vivo have been performed to investigate furan genotoxicity, the results are inconsistent, and its carcinogenic mode of...

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Identifiers

PMID: 34575853
DOI: 10.3390/ijms22189687
PMCID: PMC8465244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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