Article
A negatively charged residue stabilizes the tropoelastin N-terminal region for elastic fiber assembly.
The Journal of biological chemistry - 12 Dec 2014
Yeo Giselle C, Baldock Clair, Wise Steven G, Weiss Anthony S
Abstract excerpt
Tropoelastin is an extracellular matrix protein that assembles into elastic fibers that provide elasticity and strength to vertebrate tissues. Although the contributions of specific tropoelastin regions during each stage of elastogenesis are still not fully understood, studies predominantly recognize the central hinge/bridge and C-terminal foot as the major participants in tropoelastin assembly, with a number of...
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