Article
Structural determinants of cross-linking and hydrophobic domains for self-assembly of elastin-like polypeptides.
Biochemistry - 1 Nov 2005
Miao Ming, Cirulis Judith T, Lee Shaun, Keeley Fred W
Abstract excerpt
Elastin is a major structural protein found in large blood vessels, lung, ligaments, and skin, imparting the physical properties of extensibility and elastic recoil to these tissues. To achieve the required structural durability of the elastic matrix, the elastin monomer, tropoelastin, undergoes ordered assembly into a covalently cross-linked, fibrillar polymeric structure. Human tropoelastin consists of 34 exons...
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