Article

A synthetic elastic protein as molecular prosthetic candidate to strengthen vascular wall elasticity

2023-11-30

Abstract excerpt

The loss of elasticity is a hallmark of systemic aging or genetic syndromes (e.g. cutis laxa, Williams-Beuren and supravalvular aortic stenosis) with direct consequences on tissue functions, and particularly deleterious when associated to the cardiovascular system. Tissue elasticity is mainly provided by large elastic fibers composed of supramolecular complexes of elastin and microfibrils. In arteries, the mature...

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Literature Corpus work: 696396ff-f3ed-5ada-a695-7d69a06567f1
DOI: 10.1101/2023.11.30.569188

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