Article
Hepatitis B virus-induced hepatocellular carcinoma.
Cancer letters - 10 Apr 2014
Xu Cheng, Zhou Wence, Wang Yuming, Qiao Liang
Abstract excerpt
Many factors are considered to contribute to hepatitis B virus (HBV) associated hepatocellular carcinoma (HCC), including products of HBV, HBV integration and mutation, and host susceptibility. HBV X protein (HBx) can interfere with several signal pathways that associated with cell proliferation and apoptosis, and the impact of HBx C-terminal truncation in the development of HCC has been implicated. Recent...
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