Article
Association between three functional polymorphisms of dopamine D2 receptor gene and tardive dyskinesia in schizophrenia.
American journal of medical genetics - 8 Dec 2001
Hori H, Ohmori O, Shinkai T, Kojima H, Nakamura J
Abstract excerpt
The dopamine D2 receptor (DRD2) gene is considered one of the candidate genes contributing to the development of tardive dyskinesia (TD). In the present study, we investigated the genetic association between three functional polymorphisms (Ser311Cys, -141C Ins/Del and TaqI A) in the DRD2 gene and TD (200 patients with schizophrenia: 44 with TD and 156 without TD). No significant difference in the allelic and...
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