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Article

Genetic susceptibility to tardive dyskinesia among schizophrenia subjects: IV. Role of dopaminergic pathway gene polymorphisms.

Pharmacogenetics and genomics - 1 Feb 2006

Srivastava Vibhuti, Varma Panchami G, Prasad Suman, Semwal Prachi, Nimgaonkar Vishwajit L, Lerer Bernard, Deshpande Smita N, BK Thelma

Abstract excerpt

OBJECTIVE: Tardive dyskinesia (TD) is an antipsychotic induced side effect observed in 20-30% of schizophrenia subjects on long-term typical antipsychotic treatment. We tested the possible association of 24 polymorphisms from six dopaminergic genes: namely, dopamine receptors D1, D2, D3, D4; the dopamine transporter (DAT); and the catalyzing enzyme catechol-O-methyltransferase (COMT), with TD. METHODS: Multiple...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16424823
DOI: 10.1097/01.fpc.0000184957.98150.0f

Genes

COMT
DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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