Article
Minority drug-resistant HIV-1 variants in treatment naïve East-African and Caucasian patients detected by allele-specific real-time PCR.
PloS one - 1 Jan 2014
Ekici Halime, Amogne Wondwossen, Aderaye Getachew, Lindquist Lars, Sönnerborg Anders, Abdurahman Samir
Abstract excerpt
OBJECTIVE: To assess the presence of two major non-nucleoside reverse transcriptase inhibitors (NNRTI) drug resistance mutations (DRMs), Y181C and K103N, in minor viral quasispecies of treatment naïve HIV-1 infected East-African and Swedish patients by allele-specific polymerase chain reaction (AS-PCR). METHODS: Treatment naïve adults (n=191) with three epidemiological backgrounds were included: 92 Ethiopians...
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