Article
HIV type-1 drug resistance in treatment-naive patients monitored using minority species assays: a systematic review and meta-analysis.
Antiviral therapy - 1 Jan 2011
Buckton Andrew J, Harris Ross J, Pillay Deenan, Cane Patricia A
Abstract excerpt
BACKGROUND: The detection of mutations associated with drug resistance in HIV type-1 might be increased by applying minority species assays capable of identifying low frequency mutations in comparison with the use of population sequencing alone. Because minority species assays are mutation-specific, the benefit of this approach differs depending on the mutation being detected. METHODS: We performed a systematic...
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