Article
Associations between Genetic Variants and Angiographic Characteristics in Patients with Coronary Artery Disease.
Journal of atherosclerosis and thrombosis - 1 Jan 2015
Lee Ji-Young, Kim Gwangsil, Park Sungha, Kang Seok-Min, Jang Yangsoo, Lee Sang-Hak
Abstract excerpt
AIM: In this study, we investigated the genetic determinants of lesion characteristics and the severity of coronary artery disease (CAD) using a genome-wide association study (GWAS) and replication genotyping. METHODS: The discovery set for GWAS consisted of 667 patients exhibiting angiographically diagnosed CAD with symptoms. For replication genotyping, 837 age- and sex-matched CAD patients were selected....
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