Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Heterogeneity of the phenotypic definition of coronary artery disease and its impact on genetic association studies.

Circulation. Cardiovascular genetics - 1 Feb 2011

Kitsios Georgios D, Dahabreh Issa J, Trikalinos Thomas A, Schmid Christopher H, Huggins Gordon S, Kent David M

Abstract excerpt

BACKGROUND: Variability in phenotypic characterization of coronary artery disease (CAD) may contribute to the heterogeneity of genetic association studies, and more consistency in phenotype definitions might improve replication of genetic associations. We assessed the extent of phenotypic heterog...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coronary Artery Disease
Share to CAD gene
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Associations and Epidemiology

Share to Genetic Heterogeneity

Share to Nutrition, Genetics, and Disease

Share to Phenotype

Share to Renin-Angiotensin System Studies

Source

Open in PubMed Open full text

Identifiers

PMID: 21149552
DOI: 10.1161/CIRCGENETICS.110.957738
PMCID: PMC3048058

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21149552-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Heterogeneity of the phenotypic definition of coronary artery disease and its impact on genetic association studies.PMID 21149552Read ↗

Reproducible disease phenotyping at scale: Example of coronary artery disease in UK Biobank.Semantic proximity Read ↗

Genome-wide association studies on coronary artery disease: A systematic review and implications for populations of different ancestries.Semantic proximity Read ↗

Prevalence and Angiographic Severity of Obstructive Coronary Artery Disease in Patients Presenting with a Dilated Cardiomyopathy Phenotype: A Retrospective Single-Center Cohort StudySemantic proximity Read ↗

Identifying clinical phenotype clusters in patients with coronary artery disease.Semantic proximity Read ↗

Associations between Genetic Variants and Angiographic Characteristics in Patients with Coronary Artery Disease.Semantic proximity Read ↗

Genetic variation at the 9p21 locus predicts angiographic coronary artery disease prevalence but not extent and has clinical utility.Semantic proximity Read ↗

Impact of a Genetic Risk Score on Myocardial Infarction Risk Across Different Ethnic Populations.Semantic proximity Read ↗

Coronary Artery Disease: Association Study of 5 Loci with Angiographic Indices of Disease Severity.Semantic proximity Read ↗

Challenges in the phenotypic characterisation of patients in genetic studies of coronary artery disease.Semantic proximity Read ↗

Identification of Clinical Phenotypes in Type 2 Myocardial Infarction: Insights Into Characteristics, Prognosis, and Management StrategiesSemantic proximity Read ↗

The shared allelic architecture of adiponectin levels and coronary artery disease.Semantic proximity Read ↗

Genetic risk score of NOS gene variants associated with myocardial infarction correlates with coronary incidence across Europe.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.