Article
Paraoxonase 2 C311S single nucleotide polymorphism is associated with type C lesions in coronary atherosclerosis.
Clinical biochemistry - 1 Jan 2000
Paszek Elżbieta, Godlewski Jacek, Wołkow Paweł, Żmudka Krzysztof, Słowik Agnieszka, Legutko Jacek, Kleczyński Paweł
Abstract excerpt
BACKGROUND: Paraoxonases (PON) 1-3 are lactonases with antioxidant and atheroprotective properties. The best known single nucleotide polymorphisms (SNPs) within the PON family, include: Q192R (rs662), L55M (rs854560) in the PON1 gene and C311S (rs7493) in the PON2 gene. Their influence on the occurrence and course of coronary artery disease (CAD) is unclear. The aim of this study was to assess the association...
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