Article
Evaluation of the association of genetic variants on the chromosomal loci 9p21.3, 6q25.1, and 2q36.3 with angiographically characterized coronary artery disease.
Atherosclerosis - 1 Jul 2009
Muendlein Axel, Saely Christoph H, Rhomberg Simone, Sonderegger Gudrun, Loacker Stephan, Rein Philipp, Beer Stefan, Vonbank Alexander, Winder Thomas, Drexel Heinz
Abstract excerpt
OBJECTIVES: The chromosomal loci 9p21.3, 6q25.1, and 2q36.3, represented by their respective leading variants rs1333049, rs6922269 and rs2943634, have been linked with a history of coronary artery disease (CAD) by genome-wide association studies. Whereas the association of variant rs1333049 with CAD was analysed in several subsequent studies, replication studies of variants rs6922269 and are missing....
