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Article

Nonvalidation of reported genetic risk factors for acute coronary syndrome in a large-scale replication study.

JAMA - 11 Apr 2007

Morgan Thomas M, Krumholz Harlan M, Lifton Richard P, Spertus John A

Abstract excerpt

CONTEXT: Given the numerous, yet inconsistent, reports of genetic variants being associated with acute coronary syndromes (ACS), there is a need for comprehensive validation of ACS susceptibility genotypes. OBJECTIVE: To perform an extensive validation of putative genetic risk factors for ACS. DESIGN, SETTING, AND PARTICIPANTS: Through a systematic literature search of articles published before March 10, 2005, we...

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Identifiers

PMID: 17426274
DOI: 10.1001/jama.297.14.1551

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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