Article
Spontaneous HBsAg loss in Korean patients: relevance of viral genotypes, S gene mutations, and covalently closed circular DNA copy numbers.
Clinical and molecular hepatology - 1 Sept 2014
Kim Kyun-Hwan, Chang Hye-Young, Park Jun Yong, Park Eun-Sook, Park Yong Kwang, Han Kwang-Hyub, Ahn Sang Hoon
Abstract excerpt
BACKGROUND/AIMS: Occult HBV infection can persist following HBsAg loss and be transmitted, but the virological features are not well defined. METHODS: Here we investigated 25 Korean patients who lost HBsAg during follow up, either spontaneously or subsequent to therapy. RESULTS: Whereas subtype adr (genotype C) was found in 96% of HBsAg positive patients, 75 % of patients who lost HBsAg spontaneously were seemed...
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