Article
Occult infection related hepatitis B surface antigen variants showing lowered secretion capacity.
World journal of gastroenterology - 14 Feb 2015
Kim Hong, Lee Seoung-Ae, Won You-Sub, Lee HyunJoo, Kim Bum-Joon
Abstract excerpt
AIM: To elucidate the molecular mechanisms underlying hepatitis B virus (HBV) occult infection of genotype C. METHODS: A total of 10 types of hepatitis B surface antigen (HBsAg) variants from a Korean occult cohort were used. After a complete HBV genome plasmid mutated such that it does not express HBsAg and plasmid encoding, each HBsAg variant was transiently co-transfected into HuH-7 cells. The secretion...
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