Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptional Profiling of Mycobacterium tuberculosis Exposed to<i>In Vitro</i>Lysosomal Stress

22 Jun 2016

Abstract excerpt

Increasing experimental evidence supports the idea that Mycobacterium tuberculosis has evolved strategies to survive within lysosomes of activated macrophages. To further our knowledge of M. tuberculosis response to the hostile lysosomal environment, we profiled the global transcriptional activity of M. tuberculosis when exposed to the lysosomal soluble fraction (SF) prepared from activated macrophages....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibiotic Resistance in Bacteria
Share to Mycobacterium research and diagnosis
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27324481
DOI: 10.1128/iai.00072-16

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptional Profiling of Mycobacterium tuberculosis Exposed to<i>In Vitro</i>Lysosomal StressPMID 27324481Read ↗

Metabolic switching and cell wall remodelling of <i>Mycobacterium tuberculosis</i> during bone tuberculosisSemantic proximity Read ↗

Stress-responsive <i>Mycobacterium tuberculosis</i> subpopulations manipulate macrophage polarization and can be targeted to limit inflammationSemantic proximity Read ↗

Candidate transmission survival genome of <i>Mycobacterium tuberculosis</i>Semantic proximity Read ↗

The transcriptome of Mycobacterium tuberculosis in a lipid-rich dormancy model through RNAseq analysisSemantic proximity Read ↗

Impact of the elderly lung mucosa on <i>Mycobacterium tuberculosis</i> metabolic adaptation during infection of alveolar epithelial cellsSemantic proximity Read ↗

MtrA regulation of essential peptidoglycan cleavage in <i>Mycobacterium tuberculosis</i> during infectionSemantic proximity Read ↗

Pathogenesis in tuberculosis: transcriptomic approaches to unraveling virulence mechanisms and finding new drug targetsSemantic proximity Read ↗

Exposure of <i>Mycobacterium tuberculosis</i> to human alveolar lining fluid shows temporal and strain-specific adaptation to the lung environmentSemantic proximity Read ↗

Time-resolved RNA-seq profiling of the infection of <i>Dictyostelium discoideum</i> by <i>Mycobacterium marinum</i> reveals an integrated host response to damage and stressSemantic proximity Read ↗

Deciphering the Proteomic Landscape of Mycobacterium tuberculosis in Response to Acid and Oxidative StressesSemantic proximity Read ↗

The <i>Mycobacterium tuberculosis</i> long-chain fatty acid resistome reveals the universal stress protein TB15.3 as essential for infectionSemantic proximity Read ↗

Cell-Envelope Remodeling as a Determinant of Phenotypic Antibacterial Tolerance in <i>Mycobacterium tuberculosis</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.