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Article

Low frequency of HNPCC-associated microsatellite instability and aberrant MMR protein expression in early-onset bladder cancer.

American journal of clinical pathology - 1 Nov 2014

Giedl Johannes, Schneckenpointner Roland, Filbeck Thomas, Ruemmele Petra, Hofstaedter Ferdinand, Burger Maximilian, Hartmann Arndt, Stoehr Robert

Abstract excerpt

OBJECTIVES: Recently, it was shown that patients with Lynch syndrome due to an MSH2 mutation are at increased risk for the development of bladder cancer. To further this discussion, we screened the largest investigated cohort of patients with early-onset bladder cancer for microsatellite instabil...

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Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25319978
DOI: 10.1309/AJCPVTCJ4VU5HKVZ

Genes

MSH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25319978-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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