Article
Clinicopathological characteristics of patients with upper urinary tract urothelial cancer with loss of immunohistochemical expression of the DNA mismatch repair proteins in universal screening.
International journal of urology : official journal of the Japanese Urological Association - 1 Feb 2018
Urakami Shinji, Inoshita Naoko, Oka Suguru, Miyama Yu, Nomura Sachio, Arai Masami, Sakaguchi Kazushige, Kurosawa Kazuhiro, Okaneya Toshikazu
Abstract excerpt
OBJECTIVES: To assess the detection rate of putative Lynch syndrome-associated upper urinary tract urothelial cancer among all upper urinary tract urothelial cancers and to examine its clinicopathological characteristics. METHODS: A total of 143 patients with upper urinary tract urothelial cancer who had received total nephroureterectomy were immunohistochemically stained for the expression of mismatch repair...
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