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Article

Microsatellite instability and hMLH1/hMSH2 expression in young endometrial carcinoma patients: associations with family history and histopathology.

International journal of cancer - 1 Apr 2000

Parc Y R, Halling K C, Burgart L J, McDonnell S K, Schaid D J, Thibodeau S N, Halling A C

Abstract excerpt

Endometrial cancer is the second most common malignancy in patients with hereditary nonpolyposis colorectal cancer (HNPCC). The age at diagnosis of HNPCC-associated endometrial cancer is approximately 15 years younger than for sporadic endometrial cancer. Our current study was undertaken to determine the frequency of microsatellite instability (MSI) and absence of hMLH1 or hMSH2 protein expression in young...

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Identifiers

PMID: 10728595
DOI: 10.1002/(sici)1097-0215(20000401)86:1<60::aid-ijc9>3.0.co;2-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Microsatellite instability and hMLH1/hMSH2 expression in young endometrial carcinoma patients: associations with family history and histopathology.PMID 10728595Read ↗

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Mismatch Repair Deficiency in Endometrial Cancer: Immunohistochemistry Staining and Clinical ImplicationsSemantic proximity Read ↗

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MLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas.Semantic proximity Read ↗

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